Chaos hits blue city as 12 shot overnight in one of year’s worst weekends: report
The nation’s capital saw one of its most violent weekends of the year after 12 people were shot across the city over the span of just nine hours, police said.
The violence in Washington, D.C., began on Friday at around 5:30 p.m., after a teenage girl was shot on southeast Yuma Street, FOX 5 reported. Just 15 minutes later, a teenage boy was reportedly struck by a bullet on 50th Street.
Two hours later, a man was shot on 16th Street in the northwest area of the city.
1 DEAD, 4 WOUNDED AFTER SHOOTING IN NEW YORK CITY, POLICE SAY
At 8:18 p.m., a 5-year-old boy’s face was grazed by a bullet while on Savannah Terrace in the southeast, according to FOX 5.
The violence continued just minutes later, when three men, one woman and a teenage boy were shot just steps from Howard University’s campus, as the school was hosting a homecoming event.
While none of the victims were students at the school, one individual is reportedly enrolled at Maryland’s Morgan State.
DC VIOLENCE HAS GROWN FAR MORE DEADLY, DESPITE DEMS CLAIMING 30-YEAR LOW
Police arrested two 19-year-old suspects and recovered three guns in connection with the shooting at the university, according to FOX 5. However, authorities said more individuals may have been involved.
As the night continued, two men were reportedly shot on Benning Road in the city’s northeast area.
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Hours later, on Saturday morning, another man was critically injured after being shot on Hiatt Place in the northwest, the outlet reported.
The carnage comes as President Donald Trump has continued to deploy the National Guard throughout the city in an effort to curb instances of violent crime plaguing residents throughout the nation’s capital.
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Police are continuing to search for suspects connected to each shooting, with the weekend marking one of the most crime-ridden stretches since the year began, FOX 5 reported.
The Metropolitan Police Department did not immediately respond to Fox News Digital’s request for comment.
Vice President Vance to honor Charlie Kirk at Ole Miss Turning Point USA event
Vice President JD Vance is set to take questions at a Turning Point USA event at the University of Mississippi on Wednesday in honor of his late friend, Charlie Kirk.
Vance will be joined by Turning Point USA president Erika Kirk, Kirk’s widow, as part of the “This Is the Turning Point” campus tour. Erika Kirk is expected to introduce Vance before he takes questions and holds discussions with students in the style popularized by her husband.
Admission to the event is free, but participants are required to register in advance before attending, with students receiving priority entry. Attendants will also go through what organizers described as “TSA-style screening and magnetometer checks” once the doors open at 3 p.m. CT. The event is scheduled to begin at 5 p.m. CT.
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Fox News will also air the event live from the Ole Miss campus on “Jesse Watters Primetime.”
The full event will be streamed live on Fox Nation, followed by the premiere of a multi-part limited edition documentary series on Friday, Nov. 7, featuring behind-the-scenes footage.
Fox News Digital reached out to Turning Point for comment.
Vance confirmed he would be appearing at Ole Miss as part of the organization’s campus tour during a special appearance on “The Charlie Kirk Show” earlier this month.
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“Part of keeping Charlie’s memory alive is keeping the mission alive,” Vance said. “And nobody can replace Charlie, but if we all just sort of take little pieces, we can do as much as we can to ensure that Charlie’s mission continues to survive long after he’s gone. And part of that is these college campus tours.”
Vance was close friends with the conservative activist, who was assassinated last month on the campus of Utah Valley University.
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“I think that engagement is something that was such a big part of Charlie’s legacy,” Vance said. “It’s not just that he went and talked to people or talked about issues he cared about. It’s that he actually interacted with people.”
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The Ole Miss event is the only Turning Point USA event that Erika Kirk will attend on the campus tour. She will later conduct her first sit-down interview since her husband’s assassination with Fox News host Jesse Watters, set to air on Nov. 5.
German activist known for views on climate seeks US asylum, citing political persecution
German activist Naomi Seibt, dubbed the “Anti-Greta” by Europeans, has filed for political asylum in the U.S., claiming she’s being persecuted in her native country for her political views and advocacy of free speech.
Seibt, 25, submitted her petition under Section 208 of the Immigration and Nationality Act, stating that returning to Germany would expose her to imprisonment or physical harm.
“I have now applied for asylum, which means that I’m waiting for an interview. And, in the meantime, I’m here legally,” Seibt told Fox News Digital.
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“My goal in the meantime is to become an American citizen in the future because this country has given me so much hope,” she added, claiming her activism efforts caught Elon Musk’s attention.
“I made a post during the European elections in June 2024, where I said, my name is Naomi Seibt, and I’m voting for the AfD and that was the very first time that Musk interacted with me. Elon privately messaged me on x about the AfD.”
The move arrives amid a policy shift under President Donald Trump’s refugee and asylum agenda, which is to prioritize applicants facing persecution on grounds of political speech and opposition to government censorship.
Under that mandate, certain Europeans claiming they are at risk for expressing dissenting opinions, especially on free speech grounds, could be eligible for expedited review.
Seibt’s filing positions her as one of the first to invoke that framework. She claims to fear detention or worse if she returns to Germany, where she says she has been surveilled, threatened and left unprotected by state authorities “for years.”
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“In 2024, I found out that I had been spied on by German intelligence for years. Simultaneously, I keep receiving death threats from Antifa,” she said.
“I went to the German police, and they told me that they can’t do anything about it as long as I have not actually been raped or killed.
“I am not getting protection from the German government even though I am at major risk of potentially being killed.”
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Seibt has begun positioning herself as a free speech martyr.
“It is illegal to damage the reputation of a politician in Germany. This law was extended under Angela Merkel article 188 and now people are being arrested. And their houses are being raided for just social media posts. As soon as I come back to Germany, I feel that they will try to arrest me.”
Her activism first attracted attention when she questioned climate change orthodoxy and mass migration policies, and she was branded the “Anti-Greta” as a foil to Greta Thunberg.
“I had started becoming known and internationally recognized as the anti-Greta Thunberg in 2020,” she added.
ISRAEL CLAIMS GRETA THUNBERG’S FLOTILLA SEEKING TO BREAK GAZA BLOCKADE HAS HAMAS TIES, CITES DOCUMENTS
“I was barely 19 years old and never expected to be recognized as a right-wing figure. The German media called me the anti-Greta, they demonize me as the anti-Greta, like an anti-Christ for Greta Thunberg.
“I’m Naomi Seibt and want to be recognized as who I am because I’m not just some puppet poster figure for the right wing.”
Seibt cites close ties to billionaire Tesla founder Musk and claims he is aware of the danger in Europe, offering her support.
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“Over the course of last year, I was obviously retweeted a lot by Elon Musk, and I interacted with him personally in private messages just about what’s going on in Germany,” she explained.
“Elon has been terrified to go to Europe and knows that there is an extremely high threat and has confirmed this to me personally. That’s when I made the decision to apply for asylum myself. He gave me his approval for that.”
Couple’s dream honeymoon in Jamaica turns into nightmare as Hurricane Melissa hits
What began as a dream honeymoon has turned into a terrifying ordeal for Texas newlyweds Kasydee and Hunter Bishop, who are stranded in Jamaica as Category 5 storm Hurricane Melissa barrels toward the island, according to Fox 4 Dallas-Fort Worth.
Melissa is forecast to become the strongest hurricane in Jamaica’s history with sustained winds of 175 mph. Officials are warning of life-threatening flash flooding, landslides and widespread damage to nearby regions. Residents and visitors alike are being urged to take emergency precautions as the storm approaches.
The Bishops, who are staying in Montego Bay on the island’s northwest coast, arrived just before evacuation orders were issued, Fox 4 reported. Since then, the airport has been boarded up and all outgoing flights canceled, leaving many tourists stranded as the hurricane bears down, the station added.
“All we are hearing is how intense the storm is going to be, and we just really have no idea what to expect right now,” Hunter said, according to the local station.
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Kasydee added that she had been praying for the hurricane to not disrupt the airport and keep them from returning home. However, the couple has since moved to a shelter as the storm moves across the country.
“We feel pretty safe here at least!!” she said in a post on TikTok Monday, adding that she feels very blessed to have a place to stay. “Just praying non stop for the protection of and and everyone here!!!”
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As Melissa pushes northeast, Cuba and surrounding nations are bracing for heavy rain, flooding, storm surges and damaging winds. Areas outside the storm’s direct path are also expected to experience severe weather.
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The last time Jamaica faced a hurricane of a similar magnitude was Hurricane Gilbert in 1988, a Category 4 storm remembered as the deadliest and most destructive in the nation’s history. The storm left hundreds homeless and forced thousands into overcrowded emergency shelters, according to a report from the National Library of Jamaica. Despite its ferocity, the official death toll remained relatively low with 45 fatalities and few reported injuries, but the storm caused an estimated $800 million in damage across the island, the publication said.
Former Biden spokesperson’s ‘incoherent’ interview confuses journalists, commentators
Former White House press secretary Karine Jean-Pierre was mocked online after sitting down for an interview with The New Yorker about her new book, which critics described as “incoherent,” “entertaining” and “career-ending.”
Her book, “Independent: A Look Inside a Broken White House, Outside the Party Lines,” attacked the Democratic Party for its treatment of former President Joe Biden, who dropped out of the 2024 race after weeks of pressure from members of his own party, following a disastrous debate performance.
Political commentators and journalists posted screenshots of the interview with the New Yorker’s Isaac Chotiner, pointing to different parts of the conversation with Jean-Pierre.
Journalist Josh Barro highlighted a portion of the interview where Jean-Pierre insisted the “broken White House” she refers to in the title is President Donald Trump‘s White House.
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“You’re telling me about the feelings of Joe Biden, blah, blah, blah, but Joe Biden is out of the picture. He’s out of the picture,” Jean-Pierre told the interviewer, who said, “Yeah, he sure is.”
Chotiner pushed back, “This is what you wrote your book about. I am not bringing it up randomly.”
Jean-Pierre argued in the interview that the book was about the moment the country is in and said, “So what are the Democratic leadership actually doing to beat back and fight back? What are they doing?”
“Good Lord. Read this entire interview. It’s hard to even begin to describe Karine Jean-Pierre’s answers. They are largely incoherent,” New York Times columnist David French wrote.
French added that the former press secretary was obsessed with loyalty and respect.
Semafor’s David Weigel wrote, “Turns out you can do a career-ending interview even after your career is over.”
“Ruthless” podcast co-host Michael Duncan posted, “This is one of the most hilarious interviews I’ve ever read.”
The Atlantic’s Jonathan Chait asked, “How was KJP hired for her job in the first place?”
The National Review’s James Lynch pointed to a portion of the interview and wrote, “total gibberish.”
Chotiner pressed Jean-Pierre on her writing that she didn’t think former Vice President Kamala Harris could win, while also taking issue with people who “didn’t seem to think Harris could win by saying they were insulting her.”
“I wish you could walk in my body and live my life, and then I think you could understand what I’m saying. I really do, because I think any other Black woman would understand what I’m saying. What it truly is is that it wasn’t just an open primary or a brokered convention. There was disrespect to her as well. It was discounting her and her position and who she was. That’s what it felt like,” Jean-Pierre wrote.
“This is a very unique thing that I don’t think anyone would understand unless you walked in our bodies and lived our lives. My feeling was not about her not being qualified. It was about people not being able to see past her being Black and a woman. It’s not that confusing for us because we live this life day in and day out,” the passage continued.
KARINE JEAN-PIERRE SAYS BIDEN HEALTH TALKING POINTS WERE TIGHTLY CONTROLLED AT SENIOR LEVEL
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Jean-Pierre was also asked multiple times by Chotiner if she felt Biden could have served through January 2029.
“It’s not my place to say,” she said, as Chotiner asked what she meant by that.
“No, no, no. Wait, I’m answering the question. I did not see anything that would cause me concern. That is my answer,” Jean-Pierre added.
The former press secretary was asked about the debate and everything else people saw.
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“What I’m saying to you is the debate for me was one time. I had never seen him like that before,” she said.
Fox News Digital reached out to Jean-Pierre for comment.
Pentagon pulls protections for civilian workers in new firing guidelines memo
The Pentagon has pulled key protections for its civilian workers and instructed managers to move with “speed and conviction” to fire underperforming workers, according to a memo issued last month.
The guidelines were issued on Sept. 30, just one day before the government shutdown, in a memo titled “Separation of Employees with Unacceptable Performance” to eliminate workers with “unacceptable” performance reviews.
“Supervisors and human resources (HR) professionals are directed to act with speed and conviction to facilitate the separation from Federal service of employees performing unsuccessfully,” reads the memo signed by Under Secretary of Defense Anthony Tata, the Pentagon’s top personnel policy officer.
The memo also states that managers will be held accountable for not addressing “poor employee performance.”
PENTAGON ANNOUNCES ‘ZERO TOLERANCE’ FOR MILITARY PERSONNEL MOCKING CHARLIE KIRK’S ASSASSINATION
Some managers fear that the guidelines are too broad to where they could be used to fire anyone who does not support the Trump administration’s programs, according to The Washington Post.
It is unclear how many employees have been fired since the memo was issued last month.
“The Department is in the process of adapting to the new guidance outlined in Under Secretary of War Tata’s memo from September 30th and we have nothing specific to share at this time,” the Pentagon said in a statement to The Washington Post.
Nearly half of the Defense civilian workforce have been furloughed during the ongoing shutdown. The administration attempted to fire thousands of furloughed employees earlier this month, but the effort was blocked by a federal court.
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The civilian firings are part of a larger effort by Pentagon chief Pete Hegseth to eliminate the “debris” he purports is standing in the way of his mission to carry out Trump’s agenda.
“The sooner we have the right people, the sooner we can advance the right policies. Personnel is policy,” Hegseth said last month during a speech at Marine Corps Base Quantico.
The memo makes it easier for managers to fire Defense civilian workers, creating additional subjectivity for job performance evaluations.
Managers are directed to cite criteria used in federal job evaluations known as Douglas Factors, but each factor in the new memo added language that could impact some of those considerations.
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“Every DoW position supports the mission, so deficiencies in any role can warrant strong action,” the memo reads under the Douglas Factor section that involves an employee’s roles and responsibilities.
The factors allow managers “flexibility to address performance issues swiftly and effectively,” according to the memo.
“This approach empowers supervisors to act decisively when performance undermines DoW’s objectives, reinforcing a culture of excellence. Supervisors are to use the Douglas Factors in consideration of their action,” the memo added.
Experts put NY townhouse owners on alert if Democratic socialist becomes mayor
Real estate experts are sounding the alarm over what could happen to New York City townhouse owners if mayoral candidate Zohran Mamdani wins the election.
The self-described “Democratic socialist” has taken the city by storm with a housing platform that includes a rent freeze and higher taxes on top earners. The so-called “Mamdani Effect” has rippled through the city since his campaign began, with Manhattan’s suburban housing markets seeing a surge in demand.
“Everybody is gearing up for sellers of townhouses, in particular,” Dolly Lenz, CEO of Dolly Lenz Real Estate, said Tuesday on “The Claman Countdown.” “Imagine you own a townhouse in New York. … He says he’s going to reduce police. You don’t want to be in a townhouse. You want to be in a doorman building, right? So that is a problem.”
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Jenny Lenz, managing director at Dolly Lenz Real Estate, explained that consumers are “a little hesitant right now” and opting to rent instead of buy while waiting to see what’s next.
Mamdani’s campaign has centered on affordability and redistribution of wealth — ideas that have resonated with some New Yorkers, according to previous reports. The Lenz mother-daughter duo noted that affordability remains a top issue for Americans as home prices continue to rise compared to pre-COVID levels.
“We’re 53% higher. That is a staggering number,” Jenny said. “We’ve had 27 straight months of price increases, and the median home price is about $415,000 now. So that’s really the issue, right? But at the same time, like we said, mortgage rates are coming down. So, we are seeing our friends and clients dip their toes back into the market, which is super exciting.”
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Americans “voting with their feet” has reshaped the housing market as blue states rebound in real estate.
“It’s because everybody fled, everybody’s coming back, and prices have bottomed,” Dolly told FOX Business. “So, you’re looking at any place like New York — pricing has bottomed. Looking at Florida, Florida’s expensive. So, there’s not as much transaction volume; however, prices remain very high.”
Jenny added that areas where Americans once fled are “not doing well” because many residents have since returned.
“Developers went down there — to Florida, to Texas — and built and built and built, maybe a little too much,” she said. “Now, people are moving back. So, you’re seeing more deals in those markets, except in areas with very limited supply, like Palm Beach.”
Other consumers, the experts said, are trying to balance both experiences — living in Florida and New York — by downsizing one home and buying another.
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As first-time homebuyers reenter the market, real estate experts say a Federal Reserve rate cut would help.
“Any mortgage reduction is welcome, obviously, and a Fed rate cut is welcome,” Dolly said. “I have news for Jerome Powell: Kindly, please make it two this year. We need it, and it’s good for the economy, it’s going to be good for everyone. It trickles down all the way through the system.”
Plus-size model ‘frozen’ after flight attendant’s alleged 10-minute lecture about her weight
Plus-size model Tess Holliday said this week that she was recently told to lose weight by a flight attendant, and it left her in a “state of shock.”
The 40-year-old said she was flying first class on United from Tampa, Florida, with her 9-year-old son when she got up to use the airplane bathroom.
“I was in the restroom, and my hip hit the flight attendant call button,” she told People magazine. “When I came out of the bathroom, the flight attendant then started to tell me that they noticed I was traveling with my child, and that losing weight would be in my best interest.”
She said he continued to tell her about his sister whom he said was “very, very large, probably [Holliday’s] size,” who had been discriminated against on a flight recently.
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“He said that his sister needed to lose weight as well, and that the long-term effect on our bodies isn’t good for our health,” she said. “This went on for about 10 minutes, and I think I was just frozen. I didn’t want to make a scene because my son was flying with me, but I was also in a state of shock.”
Holliday said in a TikTok video that it was also an important flight for her son because it was his first time flying first class since he was little.
“He had flown when he was a baby, but didn’t remember, so this was a really exciting experience for him,” she explained.
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She said in the video that the flight attendant mentioned that someone had filed a complaint to United against his sister for her weight, and that United reached out to him and said things about his sister that “made him uncomfortable,” but he did “agree that she did need to lose weight.”
The Cosmopolitan UK cover girl said the flight attendant allegedly told her that he saw she was traveling with her child “and that if I cared about my child that I would do something, that I would lose the weight.”
“He then goes on to tell me that because of my size, I am kidding myself if I think that I don’t need to lose weight,” she claimed.
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Holliday said she knows that people hearing her story might think he was just trying to be helpful.
“That’s not the point,” she stressed. “You don’t say things like that to people. He said a myriad of other things. The conversation lasted entirely too long. Thankfully, I excused myself from the conversation when another passenger came up to use the bathroom.”
At the end of the video, she added that the same flight attendant came around to her seat offering snacks and allegedly gave her son gummies to keep him from being “tempted.”
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In a comment after the video, Holliday said that she had “talked to United, and they said that they would pass it along and talk to the team member. I also told them I don’t want anyone losing their job. I just want them to be aware and maybe do some sensitivity training so it doesn’t happen again.”
Fox News Digital has reached out to a rep for Holliday for comment. United had no comment for Fox News Digital.
Anti-aging supplement could slow disease and keep you younger, with some cautions
A small molecule has been hailed as potentially promoting longevity and combating certain diseases — but experts are also calling for more research.
Nicotinamide adenine dinucleotide (NAD+) — often nicknamed the “fountain of youth” — is a coenzyme that is essential for cellular survival, which naturally declines with age. In recent years, supplements designed to boost NAD+ levels have grown in popularity.
Last month, researchers led by the University of Oslo reviewed preclinical and clinical studies investigating the link between NAD+ and aging.
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The review, which was published in the journal Nature Aging, concluded that restoring NAD+ levels could help to promote healthy aging and potentially slow or treat neurodegenerative diseases.
Every cell in the body contains NAD+, which plays a “critical role” in body functions that are essential to survival.
Previous research has shown that patients with Alzheimer’s disease exhibit “notably low levels” of NAD+, the researchers noted — which aligns with the fact that NAD+ declines with age.
“NAD+ may hold the key to healthier aging and could protect us against diseases like Alzheimer’s disease and Parkinson’s disease,” said Evandro Fei Fang-Stavem, an associate professor at the University of Oslo, in a press release. “However, we need further research on how to effectively utilize NAD+ in patient treatment.”
Benefits of NAD+
Research has shown that boosting NAD+ can improve mitochondrial and stem cell function, improve energy metabolism, enhance focus and mood, and support tissue repair, according to Dr. Amanda Kahn, a board-certified internist and longevity expert in New York City.
“From a longevity standpoint, NAD+ is one of the most central molecules in maintaining youthful cellular function,” she told Fox News Digital. “It activates … longevity pathways that protect against DNA damage and inflammation.”
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Boosting NAD+ also supports neuroprotection from Alzheimer’s and Parkinson’s, enhances insulin sensitivity, reduces inflammation, repairs skin, boosts immune defense and improves symptoms in long COVID patients, Kahn added.
Dr. Halland Chen, a double board-certified physician in New York who specializes in longevity, reiterated that studies in both animals and early human models show that maintaining healthy NAD+ levels can improve energy metabolism, cognitive function and overall vitality.
“Restoring NAD+ is ultimately about cellular repair and mitochondrial optimization, not just an energy boost,” he told Fox News Digital. “Clinical experience shows that NAD+ therapy enhances energy, focus and endurance, while supporting detoxification and reducing oxidative stress from daily life, travel or poor sleep.”
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NAD+ also activates sirtuins, a group of longevity-related proteins that regulate DNA repair, cellular stress responses and gene expression, Chen said, although he noted that larger human studies are still needed.
Methods of boosting NAD+
In clinical studies, patients with age-related diseases have taken compounds designed to boost NAD+.
While NAD+ itself is a large molecule that can’t cross into cells, NAD+ “precursors” can enter cells and then work to create NAD+, experts confirm.
These precursors include nicotinamide riboside (NR) and nicotinamide mononucleotide (NMN). Most people take these NAD+ precursors in the form of pills, capsules or powders.
“Clinical experience shows that NAD+ therapy enhances energy, focus and endurance while supporting detoxification.”
“Oral NAD precursors can modestly raise NAD+ levels and are convenient for daily maintenance,” Kahn said. “In contrast, injections or IV infusions bypass the gut and deliver NAD+ directly into circulation, leading to more rapid and noticeable effects on energy, focus and recovery.”
Kahn also prescribes a weaker NAD+ nasal spray for patients who can’t tolerate needles, though she said the benefits are typically less pronounced.
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“In general, I find that combining daily oral precursors with weekly NAD+ injections offers the most comprehensive support for both intracellular and extracellular NAD stores,” she advised.
Chen noted that oral supplements are best for maintenance, while IV therapy is often chosen for a “rapid cellular reboot, post-travel recovery or enhanced performance.”
“Sessions typically last two to four hours and are administered as a series of three infusions within seven to 10 days, followed by monthly maintenance.”
NAD+ therapy tends to have the most benefit for those managing fatigue, metabolic dysfunction or neurological decline, as well as anyone seeking to enhance energy, focus and recovery, Chen said.
“In healthy adults, benefits are typically modest, but can be amplified when combined with optimized nutrition, exercise and sleep,” he added.
Risks and caveats
While NAD+ therapy is generally safe and well-tolerated, it can cause some mild side effects, according to Chen.
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“Headache, nausea or chest tightness can occur, especially during faster IV infusions, and typically resolve when the rate is slowed,” Chen, who is also chief medical innovation officer at the digital wellness platform Eden, told Fox News Digital.
“Most reactions are transient and self-limited, and therapy is considered safe under medical supervision,” the doctor added.
He advises caution for people with active liver or kidney disease, those with a personal or family history of cancer, and women who are pregnant or breastfeeding.
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Kahn noted that common side effects include mild redness, itching or tenderness at the injection site, “which is harmless and dissipates quickly.”
“Some patients notice a transient rush, lasting no more than 10 minutes, after taking an NAD+ injection due to a brief release of adrenaline and mitochondrial ATP,” she went on. “While not dangerous, it can feel uncomfortable if not anticipated.”
“If the core pillars — sleep, movement, nutrition, metabolic balance and stress regulation — are not in place, NAD+ therapy won’t deliver its full potential.”
When choosing a NAD+ product, quality matters more than quantity, according to multiple experts.
“Patients should look for clinically validated, third-party-tested formulations and start with lower doses to gauge tolerance,” Chen said.
NAD+ therapy isn’t a shortcut to health and longevity in and of itself, but one layer of a much larger foundation, according to the expert.
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“If the core pillars — sleep, movement, nutrition, metabolic balance and stress regulation — are not in place, NAD+ therapy won’t deliver its full potential,” he said. “It’s like pouring premium fuel into an engine that hasn’t been maintained — the energy source is there, but the system isn’t optimized to use it.”
It’s important to speak with a doctor before starting a NAD+ regimen, experts agree.
“Your doctor needs to know about all supplements you plan to take, including NAD+, because it has strong biological effects,” Chen said. “Your doctor will evaluate your personal health risks and check your medications for potential interactions with NAD+ supplements.”
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Kahn noted that because NAD+ interacts with metabolic and cellular pathways, dosing and timing should be individualized — “especially for those with cancer history, metabolic conditions or multiple medications.”
“A physician should help determine the appropriate delivery method, duration and monitor for response and tolerance,” she said.